Developmental Cell
Volume 47, Issue 4, 19 November 2018, Pages 400-401
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Strengthening Microtubules by Cuts that Heal

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Microtubule-severing enzymes, which can remove tubulin dimers from microtubule lattices, participate in cytoskeletal remodeling in various contexts. A recent study showed that partially damaged microtubule shafts and new microtubule ends generated by these enzymes can incorporate GTP-tubulin and serve as sites of microtubule rescue and re-growth, explaining how severing enzymes can amplify microtubule arrays.

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