Developmental Cell
Volume 24, Issue 4, 25 February 2013, Pages 340-341
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Nerve Control of Blood Vessel Patterning

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Patterning of embryonic blood vessels occurs in association with nerves. In this issue of Developmental Cell, Li et al. (2013) report that nerve-derived chemokine Cxcl12 (also known as SDF-1), acting through its receptor Cxcr4, initiates blood vessel remodeling along cutaneous nerve trajectories to establish the proper pattern of cutaneous arteries.

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