Interleukin-21 expanded NKDC in vitro reduces the B16F10 tumor growth in vivo
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Highlights
► IL-21 increases specifically the NKDC population in spleen purified DC culture supplemented with this cytokine. ► NKDCs expanded with IL-21 produce IFN-γ. ► The effector function of NKDCs against tumor growth is improved when these cells are treated with IL-21.
Keywords
Interleukin-21
Natural killer dendritic cells
Tumor
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