Current Biology
Volume 22, Issue 10, 22 May 2012, Pages 915-921
ReportKendrin Is a Novel Substrate for Separase Involved in the Licensing of Centriole Duplication
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Highlights
► Kendrin is directly cleaved by separase at a consensus site during mitosis ► The cleaved kendrin is released from centrosomes after a short lag ► Centriole disengagement coincides with a decrease in the kendrin signal ► Noncleavable kendrin expression suppresses centriole disengagement and duplication
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