Systematic Review/Meta-analysisA Systematic Review of the Diagnostic Accuracy of Cardiovascular Magnetic Resonance for Pulmonary Hypertension
Section snippets
Selection criteria
Studies relevant to the diagnosis of PH will be included.
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Type of study: Diagnostic accuracy test.
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Patients: Patients suspected of having PH and older than 18 years.
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Intervention: CMR.
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Comparison: RHC.
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Outcomes: (1) The most important index includes ventricular mass index (VMI), ratio of the pulmonary artery (PA) diameter to ascending aorta diameter (PA/AO); (2) the time interval between CMR and RHC is less than 1 month during which the clinical situation and treatment of the patient cannot be
Results
The results of the study search and screening are displayed in Figure 1. A total of 344 abstracts were identified from the electronic searches and reference lists for preliminary review. Of the 344 potential studies, 138, 49, 0, 53, 42, 33, and 29 studies were searched from PubMed, Embase, Cochrane library, Biosis Preview, ISI Web of Science, China National Knowledge Infrastructure, and Chongqing VIP database respectively. After removal of duplicated articles from different databases, a total
Discussion
Many modalities have been used to monitor and detect PH. Among the modalities, echocardiography is an excellent screening tool for patients with suspected PH, but echocardiography relies on geometric assumptions that are difficult to adopt for the patients with complex-shaped right ventricle.2 Also, the diagnostic accuracy of echocardiography depends on several variables such as detectable tricuspid regurgitation, body habitus, coexisting lung disease, heart rate, posture, and hydration status.
Funding Sources
This study was supported by a grant of the China Key Research Projects of the 12th National Five-Year Development Plan (2011BA11B17) and Beijing Training Plan of Top-notch Personnel (CIT&TCD201304189). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the report.
Disclosures
The authors have no conflicts of interest to disclose.
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2020, IJC Heart and VasculatureCitation Excerpt :A study by Seba et al. found VMI assessment of PH by MRI has a higher accuracy as compared to pressure assessment of TTE [12]. A meta-analysis by Wang et al. also used VMI as a measure and found to have high pooled sensitivity (84%) and specificity (82%)[11]. Our meta-analysis included 6 studies to assess the diagnostic accuracy of MRI using both RA pulsatility (below 40%) and VMI (>0.45).
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2015, Canadian Journal of CardiologyCitation Excerpt :The RV mass was not measured in our study. This is a time-consuming measurement, and although numerous studies have favoured it, other studies including a recent meta-analysis have challenged its usefulness for the detection of PH.17,29 We did not study other CMR findings including strain measurements, PA vortex analysis, diastolic function analysis, and gadolinium late enhancement that might have diagnostic value.5,14,30 It was not our aim to compare echocardiography vs CMR as a diagnostic tool for PH. Previous studies have documented a link between indices of RV function obtained using the 2 techniques, although guidelines have stressed the difficulty of obtaining reliable RVFAC values using echocardiography.
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