Sodium tanshinone IIA sulfonate: A review of pharmacological activity and pharmacokinetics
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Abbreviations
ACC
acetyl CoA carboxylase
AMPK
AMP-activated protein kinase
Ang II
angiotensin II
BKCa
large conductance Ca2+-sensitive K+ channels
CaCC
Ca2+-activated Cl− channel
CLIC1
intracellular chloride channel 1
CNS
central nervous system
COPD
chronic obstructive pulmonary disease
CPT
carnitine palmitoyltransferase
CYP
cytochrome P450
Danshen
Salvia miltiorrhiza Bge
ERK1/2
extracellular signal-regulated kinase1/2
Nrf2
nuclear factor erythroid 2-related factor 2
HMGB1
high mobility group box 1 protein
HO-1
heme oxygenase-1
ICAM-1
intercellular adhesion molecule-1, IP-RP-HPLC, ion-pair reversed-phase high-performance liquid chromatography
LC-ESI-MS/MS
liquid chromatography-electrospray ionisation-tandem mass spectrometry
LPS
lipopolysaccharides
Kv
voltage-activated potassium channel
MDV
Marek’s disease virus
MMP-9
matrix metalloproteinase 9
mAChR
muscarinic acetylcholine receptor
TNF-α
necrosis factor-alpha
NF-κB
nuclear factor kappaB
PRRSV
porcine reproductive and respiratory syndrome virus
PKG
protein kinase G
PPAR-γ
peroxisome proliferator-activated receptor-γ
SOCC
store-operated Ca2+ channels
STS
sodium tanshinone IIA sulfonate
Tan IIA
tanshinone IIA
TGF
transforming growth factor
TRPC
transient receptor potential canonical proteins
Keywords
Sodium tanshinone IIA sulfonate
Traditional Chinese medicine
Neoplasms
Cardiovascular disease
Transcription factor
Iron channel
Oxidative stress
Inflammation
Apoptosis
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© 2019 Published by Elsevier Masson SAS.