AVNP2 protects against cognitive impairments induced by C6 glioma by suppressing tumour associated inflammation in rats
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Abbreviations
NPs
nanoparticles
AVNPs
antiviral-nanoparticles
AMNPs
antimicrobial nanoparticles
SARS
severe acute respiratory syndrome
MRSA
methicillin-resistant staphylococcus aureus
LTP
long-term potentiation
PSD-95
postsynaptic density-95
SYP
synaptophysin
IL-1β
interleukin-1β
IL-6
interleukin-6
TNF-α
tumour necrosis factor-α
ELISA
enzyme linked immunosorbent assay
WB
western blot
VEGF
vascular endothelial growth factor
BDNF
brain derived neurotrophic factor
NF-ĸB
nuclear factor kappa-light-chain-enhancer of activated B cells
iNOS
inducible nitric oxide synthase
COX-2
cyclooxygenase-2
GBM
glioblastoma
TAMs
tumour associated macrophages
TME
tumour micro-environment
THz
terahertz
ATR
attenuated total reflection
DMEM
Dulbecco’s modified Eagle’s medium
PBS
phosphate buffered saline
XPS
X-ray photoelectron spectroscope
FTIR
Fourier transform infrared spectroscopy
SD
Sprague-Dawley
NS
normal saline
NOFT
novel object recognition test
RI
recognition index
DI
discrimination index
T1
time 1
T2
time 2
OFT
open field test
CA1
cornu ammonis 1
TBS
theta burst stimulation
DPX
distyrene, plasticizer and xylene
BCA
bicinchoninic acid
SDS-PAGE
sodium dodecyl sulfate polyacrylamide gel electrophoresis
PDVF
polyvinylidene fluoride
TBST
tris buffered saline tween
RT
room temperature
DAPI
4,6-diamidino-2-phenylindole
SEM
standard error of the mean
ANOVA
analysis of variance
fEPSPs
field excitatory postsynaptic potentials
LSD analysis
least significant difference
ECs
endothelial cells
AD
Alzheimer disease
Keywords
C6 glioma
AVNP2
Cognitive function
Inflammation
Cited by (0)
- 1
J. Li, and M. Liu equally contributed to this study.
© 2020 The Authors. Published by Elsevier Inc.