Biochimica et Biophysica Acta (BBA) - Biomembranes
Volume 1828, Issue 9, September 2013, Pages 2121-2133
Progressive stages of mitochondrial destruction caused by cell toxic bile salts
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Graphical abstract
Abbreviations
ANT
adenine nucleotide translocator
Cyt C
cytochrome C
Cys A
cyclosporine A
FCCP
carbonylcyanide-p-(trifluoromethoxy) phenyl-hydrazone
GCDCA
glycochenodeoxycholic acid
IM
inner membrane
MβCD
methyl-β-cyclodextrin
MMP
mitochondrial membrane potential
MOMP
mitochondrial outer membrane rupture
MPT
mitochondrial permeability transition
4-MUP
4-methylumbelliferyl phosphate
OD
optical density
OM
outer membrane
PC
phosphatidylcholine
Rh123
rhodamine 123
ROS
reactive oxygen species
TCDCA
taurochenodeoxycholic acid
TUDCA
tauroursodeoxycholic acid
VDAC
voltage-dependent anion channel
ZE-FFE
zone electrophoresis in a free flow electrophoresis device
Keywords
Mitochondria
Bile salts
Cholestasis
Mitochondrial permeability transition
Liver
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