Biochimica et Biophysica Acta (BBA) - Biomembranes
Volume 1818, Issue 9, September 2012, Pages 2252-2259
Surface modified liposomes by mannosylated conjugates anchored via the adamantyl moiety in the lipid bilayer
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Graphical abstract
Schematic presentation of ConA interaction with mannosylated adamantyltripeptides anchored via the adamantyl moiety in the lipid bilayer; it does not imply any stoichiometry of the ConA–liposome complex.
Highlights
► Mannosylated 1-aminoadamantane and adamantylpeptides were incorporated in liposomes. ► DLS and AFM were used for liposome characterization. ► Mannosylated conjugates were anchored via adamantyl moiety in the lipid bilayer. ► The incorporated mannosylated adamantyltripeptides are grouped into domains. ► ConA confirmed exposure of the mannose on the liposome surface.
Keywords
Adamantane
Mannose
Liposome targeting
AFM
DLS
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