Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Volume 1743, Issues 1–2, 22 March 2005, Pages 79-85
The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL☆
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Abbreviations
IRP2
iron regulatory protein 2
IRE
iron-responsive element
HIF
hypoxia inducible factor
pVHL
von Hippel–Lindau protein
GFP
green fluorescent protein
FAC
ferric ammonium citrate
DFO
desferrioxamine
DMOG
dimethyl-oxalyl-glycine
IP
immunoprecipitation
Keywords
Iron regulatory protein
Iron-responsive element
Transferrin receptor
Ferritin
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Supported by a grant from the Canadian Institutes for Health Research (CIHR).
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