Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Volume 1822, Issue 9, September 2012, Pages 1358-1362
ReviewPeroxisomes, cell senescence, and rates of aging☆
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Highlights
► Peroxisomes synthesize and degrade reactive oxygen species. ► Catalase is a critical antioxidant enzyme with a major role in cell and organismal aging. ► Supplementation of cellular catalase may impact lifespan and alter the course of degenerative disease. ► Peroxisome function and redox balance are tied to rates of aging.
Keywords
Peroxisome
Senescence
Aging
Catalase
Reactive oxygen species
Degenerative disease
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This article is part of a Special Issue entitled: Metabolic Functions and Biogenesis of Peroxisomes in Health and Disease.
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