ORIGINAL ARTICLESynthesis and antiviral activity of some novel indole-2-carboxylate derivatives
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Graphical abstract
Compound 8f showed the highest SI value (17.1) to Cox B3 virus. Compound 14f showed both potent inhibitory activity against influenza A (IC50=7.53 μmol/L) and the highest SI value (12.1).
KEY WORDS
Indole-2-carboxylate
Broad-spectrum antiviral activity
DNA and RNA virus
SAR
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