Archives of Physical Medicine and Rehabilitation
Original researchPerformance and Self-reported Functioning of People With Chronic Idiopathic Axonal Polyneuropathy: A 4-Year Follow-up Study
Section snippets
Participants
A total of 92 persons formally diagnosed as having CIAP who visited the outpatient clinic were invited to participate in this prospective longitudinal observational study. Recruitment started in 2006 and data collection ended in 2013.
Procedure
Participants were examined at the outpatient clinic at 4 time points: baseline (T0), a half year after T0 (T1), 1 year after T0 (T3), and 4 years after T0 (T4). One week before the visit, questionnaires were sent to the participant to be completed by them at home
Participant characteristics
At T0 (baseline) we included 92 participants with CIAP; 85 participated at T1 (6mo after T0), 78 participated at T2 (1y after T0), and 65 completed all measurements at T3 (4y after T0) (table 1). A total of 27 participants (29.3%) dropped out of the study. Dropouts were because of increased comorbidity (n=7), a testimony of not willing to continue participation (n=10) and unknown reason (n=9), and 1 person died. A comparison between those who completed the study and those who dropped out showed
Discussion
This group of 92 people with CIAP revealed a gradual decline of muscle and sensory function and of performance of activities over 4 years, with a large initial interindividual variation that remained during the entire follow-up period. Previous research in people with CIAP already demonstrated a rather corresponding slow deterioration in sensory and motor function over time.6,7,11 In patients with CIAP the deterioration in performance of activities on both performance measures (SWT and step
Conclusions
Overall, we found a decrease in performance of activities over time, more than what could be related to aging only, and interindividual differences in our group of participants with CIAP.
Suppliers
- a.
MicroFET handheld dynamometer; Hoggan Health Industries Inc.
- b.
Jamar dynamometer; Therapeutic Equipment Co.
- c.
DigiWalker Step Counter; Lifestyles Inc.
- d.
SPSS version 20; IBM.
- e.
MLwiN version 2.021; Centre for Multilevel Modelling of the Institute of Education in London.
Acknowledgments
We thank Claire Huisman, BSc for her help editing the manuscript, her translations, and proofreading.
References (47)
- et al.
Osteogenesis imperfecta in childhood : impairment and disability. A prospective study with 4-year follow-up
Arch Phys Med Rehabil
(2004) - et al.
Effects of physical comorbidities on disability progression in multiple sclerosis
Neurology
(2018) - et al.
A personal view on systems medicine and the emergence of proactive P4 medicine: predictive, preventive, personalized and participatory
N Biotechnol
(2012) - et al.
Perceived control is a concurrent predictor of activity limitations in patients with chronic idiopathic axonal polyneuropathy
Arch Phys Med Rehabil
(2007) - et al.
The Berg Balance Scale has high intra- and inter-rater reliability but absolute reliability varies across the scale: a systematic review
J Physiother
(2013) - et al.
Minimal detectable changes of the Berg Balance Scale, Fugl-Meyer Assessment Scale, timed “Up & Go” test, gait speeds, and 2-minute walk test in individuals with chronic stroke with different degrees of ankle plantarflexor tone
Arch Phys Med Rehabil
(2012) Clinical assessment of balance disorders
Gait Posture
(1997)- et al.
Construct validation of the hospital anxiety and depression scale with clinical populations
J Psychosom Res
(2000) The theory of planned behavior
Organ Behav Hum Decis Process
(1991)- et al.
Neuromuscular impairments contributing to persistently poor and declining lower-extremity mobility among older adults: new findings informing geriatric rehabilitation
Arch Phys Med Rehabil
(2016)
Prevention of onset and progression of basic ADL disability by physical activity in community dwelling older adults: a meta-analysis
Ageing Res Rev
Determinants of participation in patients with severe haemophilia
Haemophilia
Incidence of polyneuropathy in Utrecht, the Netherlands
Neurology
Chronic idiopathic polyneuropathy presenting in middle or old age: a clinical and electrophysiological study of 75 patients
J Neurol Neurosurg Psychiatry
Chronic cryptogenic sensory polyneuropathy: clinical and laboratory characteristics
Arch Neurol
Chronic idiopathic axonal polyneuropathy and vitamin B6: a controlled population-based study
J Peripher Nerv Syst
Quality of life in patients with axonal polyneuropathy
J Neurol
Chronic idiopathic axonal polyneuropathy: a systematic review
J Neurol
Chronic idiopathic axonal polyneuropathy: a five year follow up
J Neurol Neurosurg Psychiatry
Progression in idiopathic, diabetic, paraproteinemic, alcoholic, and B12 deficiency neuropathy
J Peripher Nerv Syst
Developing an integrated biomedical and behavioural theory of functioning and disability: adding models of behaviour to the ICF framework
Health Psychol Rev
The international classification of functioning, disability and health: ICF
Functioning of patients with chronic idiopathic axonal polyneuropathy (CIAP)
J Neurol
Cited by (2)
Chronic inflammatory neuropathies and their impact on activities and participation
2023, European Journal of Neurology
- ∗
van Meeteren and Schröder contributed equally to this work.