Original ArticleMicrobial Keratitis in Taiwan: A 20-Year Update
Section snippets
Methods
The study conformed to the provisions of the Declaration of Helsinki and was approved by the Institutional Research Ethics Board of National Taiwan University Hospital (IRB number: 201610028RINB). We reviewed the medical records of hospitalized patients with clinically diagnosed microbial keratitis between 2007 and 2016. The following noninfectious corneal diseases were excluded: superficial injury of cornea, open wound of eyeball, corneal opacity, and cases of viral keratitis. Patient
Demographics
The demographic data are summarized in Table 1. From 2007 to 2016, a total of 370 eyes from 363 patients were identified. Seven cases had a simultaneous bilateral infection. Patients included 171 men (47.1%) and 192 women (52.9%), aged from 4 to 93 years (mean age 50.2 ± 23.3 years). The average age of the microbial keratitis population became older (40.7 ± 21.6 years in 1992-2001 vs 50.2 ± 23.3 in 2007-2016; P =3.5E-9). The age distribution in comparison with previous data from 1992 to 1996
Discussion
This study updated the microbiology data and patient demographics of microbial keratitis in Taiwan to establish reference information for clinicians. There was a slight female preponderance in our cases and the commonest risk factor documented was contact lens use, consistent with other domestic data.3, 4 This may be owing to a greater proportion of contact lens–associated keratitis composed of female patients, as previous studies suggested.5, 6 However, the absolute number of contact
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Supplemental Material available at AJO.com.