Patterns of glaucomatous visual field progression identified by three progression criteria
Section snippets
Subjects
Included in this analysis of serial visual fields were 112 eyes of 112 patients with glaucoma. The study eye was selected randomly. These patients came from two studies. The first was a prospective multicenter study in which 72 patients were followed at 3, 6, 12, 18, and 24 months. Hereafter, this group will be referred to as the “semiannual” group. Progression on visual fields was defined by the clinical criteria listed below. When progression was noted, a follow-up field was scheduled within
Results
Baseline mean deviations for abnormal and progressed visual field locations versus abnormal and nonprogressed locations were within 1.0 dB (−5.3 ± 5.6 and −4.4 ± 5.0, respectively). Eyes in the semiannual group had a minimum of four fields and a maximum of six fields. Eyes in the annual group had a minimum of four and a maximum of 17 follow-up fields.
Discussion
As has been shown in earlier studies, progression criteria comparable to those in our study do not always identify the same eyes as progressed or even the same number of progressed eyes.10, 11, 18, 24 For instance, clinical criteria for progression similar to those employed here tend to indicate more eyes as progressed than the GCP using total deviation. Additionally, the GCP using the total deviation plot tends to signal more eyes as progressed than does the GCP using pattern deviation. The
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This research was supported by a grant from the National Eye Institute, NEI EY 08208 (P.A.S.), Glaucoma Research Foundation (P.A.S.), Research to Prevent Blindness and Alcon (P.A.S.), Foundation for Eye Research (E.Z.B., F.M.). Research support from Carl-Zeiss Meditec, Inc. (P.A.S., R.N.W.).