Review article
Update in COVID-19 in the intensive care unit from the 2020 HELLENIC Athens International symposium

https://doi.org/10.1016/j.accpm.2020.10.008Get rights and content

Highlights

  • Severe COVID-19 presents as multiple organ dysfunction syndrome (SARS-CoV-2 MODS).

  • Less is more in ventilating critically ill patients with severe COVID-19 pneumonia.

  • European Medicines Agency released approval for administration of steroids.

  • Main therapeutic targets: anti-inflammatory; anticoagulation; protective ventilation.

Abstract

The 2020 International Web Scientific Event in COVID-19 pandemic in critically ill patients aimed at updating the information and knowledge on the COVID-19 pandemic in the intensive care unit. Experts reviewed the latest literature relating to the COVID-19 pandemic in critically ill patients, such as epidemiology, pathophysiology, phenotypes of infection, COVID-19 as a systematic infection, molecular diagnosis, mechanical ventilation, thromboprophylaxis, COVID-19 associated co-infections, immunotherapy, plasma treatment, catheter-related bloodstream infections, artificial intelligence for COVID-19, and vaccination. Antiviral therapy and co-infections are out of the scope of this review. In this review, each of these issues is discussed with key messages regarding management and further research being presented after a brief review of available evidence.

Keywords

COVID-19
SARS-CoV-2
Pneumonia
Acute respiratory failure
ARDS
Intensive care

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