Chapter 8 Neuroendocrine Aspects of the Aging Brain
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Cited by (2)
PPARγ and stress: Implications for aging
2013, Experimental GerontologyCitation Excerpt :Aging can also be accompanied by altered HPA axis activation in response to stress. For instance, older people may have a greater and/or more prolonged plasma cortisol response (reviewed in: Ferrari et al., 2001), and it likewise has been reported that aging rodents often exhibit an elevated and/or persistent corticosterone response to stress (Herman et al., 2001; Wise et al., 1997). This may be due in part to a reduction in glucocorticoid negative feedback that can occur during aging in both people (reviewed in: Ferrari et al., 2001), and rodents (reviewed in: Wise et al., 1997), thereby impairing the ability of the HPA axis to terminate its own response.
Chapter 1 Genetic Contributions to the Pathogenesis of Alzheimer's Disease
1999, Advances in Cell Aging and Gerontology
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