2016 Round-up
Stroke research in 2016: when more medicine is better, and when it isn't

https://doi.org/10.1016/S1474-4422(16)30332-5Get rights and content

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Cited by (6)

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    In addition to intensive medical therapy, stenting in VAO was safe and effective for preventing stroke.5,6 Although the primary endpoint (any stroke during follow-up) of Vertebral artery Ischemic Stenting Trial showed no statistical deference between stenting and medical treatment arms,7 the study would lend a perspective to the benefit from extracranial vertebral artery stenting which might reduce recurrent stroke.7-9 One of the problems for stenting in VAO is in-stent restenosis (ISR), which is induced by the excessive neointimal hyperplasia in the lumen of stent and the thrombosis in the stent.

  • Remote limb ischemic postconditioning protects against cerebral ischemia-reperfusion injury by activating AMPK-dependent autophagy

    2018, Brain Research Bulletin
    Citation Excerpt :

    Stroke is one of the most common diseases with a leading cause of high morbidity and mortality worldwide (Rothwell, 2017).

  • Editor's Choice – Management of Atherosclerotic Carotid and Vertebral Artery Disease: 2017 Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS)

    2018, European Journal of Vascular and Endovascular Surgery
    Citation Excerpt :

    A systematic review, involving 672 symptomatic patients in four RCTs and six non-randomised studies between 2007 and 2015, and which compared outcomes between percutaneous transluminal angioplasty (PTA) plus BMT versus BMT alone, observed no significant benefit from PTA + BMT over BMT alone (Table 28).459 Not included in Feng's meta-analysis was the Vertebral Artery Ischaemia Stenting Trial (VIST), which presented its results at the European Stroke Organisation Conference in 2016.460,461 VIST randomised 182 patients with symptomatic intra- and extracranial VA stenoses between BMT versus angioplasty with or without stenting.

  • Controversies in Thrombolysis

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  • Cerebral blood flow and metabolism: A quantitative approach

    2017, Cerebral Blood Flow and Metabolism: A Quantitative Approach
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