ArticlePharmacokinetics and follicular dynamics of corifollitropin alfa versus recombinant FSH during ovarian stimulation for IVF
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Cited by (7)
Current options to lower the cost of in vitro fertilization: a comprehensive review
2023, F and S ReviewsCitation Excerpt :Corifollitropin alfa is a relatively new recombinant gonadotropin preparation that has a benefit of sustained (approximately 7 days) multifollicular ovarian stimulation when compared with traditional recombinant gonadotropins. Phase II and III trials suggest the doses of 150 and 100 μg for patients weighing >60 and ≤60 kg, respectively (74). A meta-analysis recently synthesized data from 8 RCTs and found no difference in the live birth rates in patients using corifollitropin alfa when compared with patients undergoing conventional ovarian stimulation (75).
Dual stimulation using corifollitropin alfa in 54 Bologna criteria poor ovarian responders – a case series
2019, Reproductive BioMedicine OnlineCitation Excerpt :However, corroborative studies comparing the DuoStim protocol with conventional stimulation protocols are needed to draw firm conclusions. Corifollitropin alfa is used in the DuoStim protocol due to its long-lasting profile, with a half-life of 68 h and a maximal serum concentration after 44 h (Fauser et al., 2011). This pharmacokinetic profile showed its advantage compared with daily-administered rFSH in a study including Bologna POR only.
Novel physiology and definition of poor ovarian response; clinical recommendations
2020, International Journal of Molecular SciencesEvaluation of the safety and efficacy of corifollitropin alfa combined with gnrh agonist triggering in oocyte donation cycles. A prospective longitudinal study
2020, Jornal Brasileiro de Reproducao AssistidaManagement Strategies for POSEIDON Groups 3 and 4
2019, Frontiers in EndocrinologyEffectiveness of corifollitropin alfa used for ovarian stimulation of poor responder patients
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Bart CJM Fauser, MD, PhD, is Professor of Reproductive Medicine, University of Utrecht and Chair of the Woman & Baby Division at the University Medical Center, Utrecht. Previously, he was Fulbright post-doctoral scholar at the University of California, San Diego (1987-1988), Visiting Professor at Stanford School of Medicine, Palo Alto (1993-1995), Professor of Reproductive Endocrinology and director of the Center of Reproductive Medicine, Erasmus Medical Center, Rotterdam (1996-2003), editor-in-chief of Molecular Biology in Reproductive Medicine and Human Reproduction Update (2001-2007) and Saal van Zwanenberg Professor, Centre for Reproductive Medicine, Free University of Brussels (2003-2008).
Declaration: Financial support for this study was provided by Schering-Plough, now Merck, Sharp and Dohme. Editorial support was provided by P Milner, PhD, of PAREXEL and funded by Schering-Plough. BCJMF has received fees and grant support from the following companies (in alphabetical order); Andromed, Ardana, Ferring, Genovum, Glycotope, Merck Serono, Organon, Pantharei Bioscience, Philips, PregLem, Schering and Schering-Plough. MMA has received honoraria and research support from Ferring, Merck-Serono, and Schering-Plough. WL has received fees and grants from the following companies: Akzo Nobel, Ferring, Ipsen and Almirall, Merck Serono, Organon, Schering-Plough, Serono and Wyeth. WBS has received honoraria and research support from Ferring, Merck-Serono and Schering-Plough. AZ and BMJLM are employed by Schering-Plough.
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Engage investigators Belgium: Devroey, UZ Brussel, Center for Reproductive Medicine, Brussels; Dhont, University Hospital Ghent, Department of Gynecology. Canada: Leader, The Ottawa Fertility Center, Ottawa, Ontario. Czech Republic: Mardesic, Sanatorium Pronatal, Prague; Mrázek, ISCARE IVFa.s., Prague. Denmark: Blaabjerg, Herlev Hospital, Fertility Clinic, Herlev. Finland: Tapanainen, Naistentautien klinikka, Oulun yliopistollinen sairaala (OYS), Oulu; Varila, Väestöliitto, Tampereen klinikka, Tampere. France: Barrière, Hôpital de la mère et de l'enfant, Nantes; Hedon, Hôpital Arnaud de Villeneuve, Montpellier. The Netherlands: Fauser and Sterrenburg, University Medical Center, Department of Reproductive Medicine and Gynecology, Utrecht. Norway: Kahn, Sykehuset Telemark HF, Skien; Von During, St. Olavs Hospital HF, Trondheim. Spain: Bajo Arenas, Ginefiv, Madrid; Barri, Institut Universitari Dexeus, Barcelona; Fernández-Sánchez, IVI Sevilla, Sevilla. Sweden: Bergh, Kvinnokliniken, Sahlgrenska Universitetssjukhuset, Göteborg; Hillensjö, Fertilitetscentrum, Carlanderska Sjukhuset, Göteborg. UK: Balen, Assisted Conception Unit, Leeds General Infirmary; Ledger, Assisted Conception Unit, Jessop Wing, The Halllamshire Hospital, Sheffield; Matthews, Bourn Hall Clinic, Cambridge. USA: Abuzeid, IVF Michigan, Rochester Hills, Ml; Alper, Boston IVF, Waltham, MA; Boostanfar, Huntington Reproductive Center, Westlake Village, CA; Doody, Center for Assisted Reproduction, Bedford, TX; Frattarelli, Reproductive Medicine Associates of New Jersey, Morristown, NJ; Grunfeld, Reproductive Medicine Associates of New York, New York, NY; Karande, Karande and Associates SC, Hoffman Estates, IL; Kort, Reproductive Biology Associates, Atlanta, GA; Levy, Shady Grove Fertility Reproductive Science Center, Rockville, MD; Lifchez, Fertility Centers of Illinois, Chicago, IL; Pang, Reproductive Science Center of Boston, Lexington, MA; Schoolcraft, Colorado Center for Reproductive Medicine, Englewood, CO; Yeko, The Reproductive Medicine Group, Tampa, FL.