CommentCirculating tumour cells: telling the truth about metastasis
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Highly sensitive detection and mutational analysis of lung cancer circulating tumor cells using integrated combined immunomagnetic beads with a droplet digital PCR chip
2018, TalantaCitation Excerpt :During the metastasis, tumor cells, termed as circulating tumor cells (CTCs), have detached from a primary solid tumor to circulate in the bloodstream and reached another organ to form a secondary tumor. Therefore, CTCs are closely associated with tumor size, progress, metastasis, relapse and prognosis [1–4]. Analysis of CTCs in peripheral blood is important in individual treatment and prognosis of solid tumors.
Possible applications of circulating tumor cells in patients with non small cell lung cancer
2017, Lung CancerCitation Excerpt :For all these reasons, in accordance with the suggestion of Cristofanilli, the FDA and pharmaceutical industry should include the enumeration and molecular analysis of CTCs in future clinical trials, particularly when testing targeted therapies [39].
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