Chemistry & Biology
Volume 6, Issue 5, May 1999, Pages 319-331
Structure-based discovery and in-parallel optimization of novelcompetitive inhibitors of thymidylate synthase
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Key words
computer-based inhibitor design
enzymespecificity
in-parallel synthesis
structure-based drug design
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Present addresses: Dipartimento di Scienze Farmaceutiche, Università degli Studi di Modena, 183 Via Campi, Modena, Italy.
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MetaPhorePharmaceuticals Inc., 3655 Vista Avenue, St. Louis, MO 63110, USA.
Copyright © 1999 Published by Elsevier Ltd.