Translation control: Connecting mitogens and the ribosome

doi:10.1016/S0960-9822(98)70152-6

Current Biology

Volume 8, Issue 7, 26 March 1998, Pages R248-R250

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Abstract

The identification of 3-phosphoinositide-dependent kinase 1 (PDK1) as one of the elusive 70 kDa S6 kinase kinases has filled a gap in the signaling pathway by which extracellular receptors regulate translation. Will it cause us to reconsider the relationships between previously identified members of the pathway?

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RT Peterson and SL Schreiber, Howard Hughes Medical Institute, Departments of Chemistry and Chemical Biology, and Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

E-mail address for SL Schreiber: [email protected].

Current Biology

DispatchTranslation control: Connecting mitogens and the ribosome

Abstract

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Translation control: Connecting mitogens and the ribosome