Tensile properties of the neurorrhaphy site in the rat sciatic nerve*
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Cited by (19)
Comparison of Nylon Suture Versus 2 Fibrin Glue Products for Delayed Nerve Coaptation in an Animal Model
2021, Journal of Hand SurgeryCitation Excerpt :At 0, 3, and 7 days after repair, 10 rats from each group either remained anesthetized (time point 0) or were reanesthetized (days 3 and 7) and the sciatic nerve was exposed as previously described. Prior studies demonstrated that the largest gain in tensile strength after neurorrhaphy in an animal model occurs within the first week of repair; thus, we chose 7 days as the final mechanical testing time point.15,16 The sciatic nerve and tibial and peroneal nerve branches were neurolysed (including the repair site).
Biomechanical evaluation of peripheral nerves after crush injuries
2019, HeliyonCitation Excerpt :They concluded that the compressive forces applied onto nerves for a specific duration had an additive effect on top of the pressure, which caused edema and nerve fiber damage. Biomechanical properties of nerves after laceration, stretch-related, and crush injuries have been studied in order to understand the complete neurophysiological behavior of nerves after injury [4, 5, 6]. Mechanical properties such as ultimate failure, stiffness, stress, strain, and position of failure have been evaluated for both intact and repaired nerves based on rodent or rabbit model.
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2018, Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition: Volume 1-3Peripheral Nerve Interfaces
2015, Nerves and Nerve Injuries: Pain, Treatment, Injury, Disease and Future Directions: Vol 2Two pole air gap electrospinning: Fabrication of highly aligned, three-dimensional scaffolds for nerve reconstruction
2011, Acta BiomaterialiaCitation Excerpt :Peak stress in each of these constructs was greater than what was observed in scaffolds produced from 100 mg ml−1 PCL (P < 0.007). These values, with the exception of scaffolds produced from the 100 mg ml−1 solutions, compare favorably to the material properties of native rodent sciatic nerve [25]. While each scaffold is composed of highly aligned fibers, considering the variable fiber diameters, the spaces between each of the individual fibers can be expected to be very different, which would influence the penetration of regenerating axons.
Electrodes for the Neural Interface
2009, Neuromodulation
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No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article.
- 1
From the Hand and Microvascular Surgery Service, Neuromuscular Physiology Laboratory, Department of Orthopedic Surgery, University of California, San Diego; and the Department of Orthopedics. Veteran's Administration Hospital, San Diego, CA.