Heterogeneity Amongst Lymph-borne «Dendritic» Cells
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Migratory sub-populations of afferent lymphatic dendritic cells differ in their interactions with Mycobacterium bovis Bacille Calmette Guerin
2012, VaccineCitation Excerpt :In cattle, major sub-populations of skin draining ALDC with differential expression of SIRPα (CD172a), CD11a, CD26 and CD13 [6,9,11,12] interact with and stimulate T cells differently, and have differential cytokine secretion profiles [5,6,13,14]. Studies of ALDC draining the intestine of rats and the head mucosae of sheep [15–18] concluded that a major population of SIRPα− ALDC which contained cytokeratin inclusions were involved in the maintenance of peripheral tolerance [19,17]. These observations emphasise the differences and complexity of in vivo DC subsets and indicate that differing DC sub-populations may be involved in the control of the immune response.
A single step centrifugation method for the enrichment of veiled cells from canine afferent lymph
1989, Journal of Immunological MethodsComparison of membrane antigens of mouse dendritic cell types
1987, Immunology LettersIsolation of large mononuclear Ia-positive veiled cells from the mouse thoracic duct
1985, Journal of Immunological MethodsTo respond or not to respond - A personal perspective of intestinal tolerance
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G. G. MacPherson, Sir William Dunn School of Pathology, South Parks Road, Oxford OX1 3RE, U.K.