CorrespondenceConflict and drug-resistant tuberculosis in Ukraine
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Armed conflict and human displacement may lead to an increase in the burden of tuberculosis in Europe
2022, International Journal of Infectious DiseasesCharacterization of novel Mycobacterium tuberculosis pncA gene mutations in clinical isolates from the Ukraine
2019, Diagnostic Microbiology and Infectious DiseaseCitation Excerpt :Thus, use of PZA to treat patients that harbor PZA resistance may lead to development of pre-XDR and XDR-TB. Therefore, worldwide detection of pncA resistance mutations is critically important especially in RIF-resistant patients that could benefit from a PZA treatment regimen (Bellan et al., 2014; Ramirez-busby and Faramarz, 2015). However, this requires use of rapid, molecular-based PZA resistance detection which currently is not universally available.
TB control in humanitarian emergencies: Lessons from the Syria displacement crisis
2019, Journal of Clinical Tuberculosis and Other Mycobacterial DiseasesCitation Excerpt :A lesson for TB control in other humanitarian emergencies is to target screening for TB among emergency-affected populations based on the specific epidemiologic context. In cross-border mass migrations, a symptom-based screening for TB should be offered at the border or upon registration, both to identify undiagnosed active TB cases as well as those emergency-affected patients who have been on treatment for TB, to prevent the risk of transmission and development of drug-resistant disease [12–14]. A recent molecular epidemiology study found a cluster of almost 30 multi-drug resistant TB cases in Europe among persons fleeing hardship in the Horn of Africa, exemplifying the risk of TB transmission during transit, the need for screening during migration, and the need for follow-up and treatment in the country of asylum [15].
Tuberculosis: current challenges and beyond
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