Cell
ArticleEnhancer-origin interaction in plasmid R6K involves a DNA loop mediated by initiator protein
References (32)
Three origins of replication are active in vivo in the R plasmid RSF 1040
J. Biol. Chem.
(1980)- et al.
Trinodular structure of fibrinogen-confirmation by both shadowing and negative stain electron microscopy
J. Mol. Biol.
(1979) - et al.
The replication initiator protein of plasmid R6K tagged with β-galactosidase shows sequence-specific DNA binding
Cell
(1983) - et al.
Interaction of the plasmid R6K-encoded replication initiator protein with its binding sites on DNA
Cell
(1983) - et al.
Cooperative binding of λ repressors to sites separated by integral turns of the DNA helix
Cell
(1986) - et al.
A control element within a structural gene: the gal operon of Escherichia coli
Cell
(1983) - et al.
Hin-mediated site-specific recombination requires two 26 by recombination sites and a 60 by recombinational enhancer
Cell
(1985) - et al.
G inversion in bacteriophage mu DNA is stimulated by a site within the invertase gene and a host factor
Cell
(1985) - et al.
Sequencing end-labeled DNA with base-specific chemical cleavages
Meth. Enzymol.
(1980) - et al.
Conformational changes in a replication origin induced by an initiator protein
Cell
(1985)
A replication origin is turned off by an origin-“silencer” sequence
Cell
A replication initiator protein enhances the rate of hybrid formation between a silencer RNA and an activator RNA
Cell
The nucleotide sequence of the replication origin of the plasmid R6K
J. Biol. Chem.
The molecular structure of human erythrocyte spectrin
J. Mol. Biol.
Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product
Cell
Plasmid R6K DNA replication: complete nucleotide sequence of an autonomously replicating segment
J. Mol. Biol.
Cited by (97)
Plasmid R6K replication control
2013, PlasmidCitation Excerpt :π protein facilitates interaction between the iterons in γ ori and iteron-like sequences in oris α and β (Mukherjee et al., 1988b; Miron et al., 1992; Saxena et al., 2010a, 2010b). This results in a looping of the plasmid DNA, which is believed to transmit the replication signal from the internal iteron cluster (7 DRs) to the outlying R6K oris (Mukherjee et al., 1988a, 1988b). Studies of the interaction between γ and α oris suggest that both monomers and dimers of π protein participate in the looping process (Saxena et al., 2010a, 2010b).
Regulation of Replication Termination by Reb1 Protein-Mediated Action at a Distance
2010, CellCitation Excerpt :We wished to confirm the aforementioned ligation enhancement results by an independent method. The method is schematically shown in Figure 3A (Mukherjee et al., 1988; Zzaman and Bastia, 2005). The plasmid DNA substrate pSW1 contained a M7 and a WT Ter site cloned on either sides of the unique EcoR1 site.
Investigations of π initiator protein-mediated interaction between replication origins α and γ of the plasmid R6K
2010, Journal of Biological ChemistryCitation Excerpt :The replication origins α and β are located ∼3800 and ∼1200 bp away, respectively, from ori γ and at its opposite side (11, 15). We have previously reported that π-mediated DNA looping between the single iteron at α or the half-iteron at β with the γ iteron array appears to activate the two distantly located origins, respectively (9, 13, 16). Models of activation of each of the three origins, that are mutually exclusive, and the postulated looped structures involved in the process are shown in Fig. 1.
Cooperative Binding Mode of the Inhibitors of R6K Replication, π Dimers
2008, Journal of Molecular Biology