The myopic growth process has the potential to modify both the optical and neural performance of the eye. We provide three simple models, based on different types of retinal stretching, to predict changes in neural resolution resulting from axial length increases in myopia. These predictions are compared to visual acuity (VA) measures in 34 subjects with refractive errors ranging from plano to −14 D. Our results show a reduction in VA with increasing myopia but not in a manner predicted by our models. We discuss the relative contribution of optical and neural factors to the reduction in visual resolution in myopia.