Elsevier

Tetrahedron Letters

Volume 41, Issue 42, 14 October 2000, Pages 8041-8044
Tetrahedron Letters

An efficient Rh-catalyst system for the intramolecular [4+2] and [5+2] cycloaddition reactions

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Abstract

A new Rh-catalyst system has been developed for the [4+2] and [5+2] cycloaddition reactions. This new system shows high reactivity at room temperature and the Rh-center bears tunable phosphine ligands. Up to 1000 turnovers have been obtained for the [4+2] cycloaddition reaction at room temperature.

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Acknowledgements

This work was supported by the DuPont Young Faculty Award and the NIH (1R01 GM58832-01A1). We acknowledge a generous loan of precious metals from Johnson Matthey Inc.

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