Elsevier

Phytochemistry

Volume 26, Issue 2, 28 January 1987, Pages 467-470
Phytochemistry

Five grindelane diterpenoids from Grindelia acutifolia

https://doi.org/10.1016/S0031-9422(00)81434-XGet rights and content

Abstract

Five new labdane diterpenoid acids, 6α-hydroxy-17-acetoxygrindelic acid, 6-oxo-17-acetoxygrindelic acid, 6α-hydroxy-17-isovaleroxygrindelic acid, 6α-hydroxy-17-(α-methylbutyroxy)grindelic acid and 6-oxo-17-isobutyroxygrindelic acid, were shown to be present in Grindelia acutifolia, mainly on the basis of comparisons of the spectra of their methyl ester derivatives with those of their 6-deoxy derivatives, several of which are major constituents of this plant species.

References (7)

  • B.N. Timmermann et al.

    Phytochemistry

    (1983)
  • F. Bohlmann et al.

    Phytochemistry

    (1982)
  • B.N. Timmermann et al.

    Phytochemistry

    (1985)
There are more references available in the full text version of this article.

Cited by (19)

  • Synthesis and cholinesterase inhibition of cativic acid derivatives

    2014, Bioorganic and Medicinal Chemistry
    Citation Excerpt :

    The genus Grindelia (Asteraceae) is represented in South America by 26 species, 23 of them endemic.12 Plants from this genus are known to be sources of bioactive compounds, mostly diterpenoids of the labdane type and manoyl oxide derivatives, mono- and sesquiterpenes, polyacetylenes, flavonoids, and saponins.13–24 Anti-inflammatory, expectorant, antispasmodic, and antimicrobial activities, as well as antifeedant effects towards insects, have been reported for extracts or secondary metabolites obtained from Grindelia plants.17,22–27

View all citing articles on Scopus
View full text