Short communicationStereological evaluation of substantia nigra cell number in normal and hemispherectomized monkeys
Section snippets
Acknowledgements
This work was supported by grants from the National Science and Engineering Research Council of Canada (NSERC) and from FCAR (Québec).
References (26)
- et al.
The functional anatomy of basal ganglia disorders
Trends Neurosci.
(1989) - et al.
The neurobiology of blindsight
Trends Neurosci.
(1991) - et al.
Sparing of visual field perception in neonatal but not adult cerebral hemispherectomized cats. Relation with oxidative metabolism of the superior colliculus
Behav. Brain Res.
(1990) - et al.
A stereological study of substantia nigra in young and old rhesus monkeys
Brain Res.
(1995) - et al.
Neural bases of residual vision in hemicorticectomized monkeys
Prog. Brain Res.
(1996) - et al.
Eye movements in an adult with cerebral hemispherectomy
Am. J. Ophtal.
(1956) - et al.
Extrageniculate vision in humans: investigations with hemispherectomy patients
Prog. Brain Res.
(1996) - et al.
Effects of aging on the size, density, and number of rhesus monkey lateral geniculate neurons
J. Comp. Neurol.
(1993) - et al.
Investigations of the anatomical basis of blindsight: an fMRI study of hemispherectomized patients
Hum. Brain Map.
(1998) - et al.
The total number of neurons in the human neocortex unbiasedly estimated using optical disectors
J. Microsc.
(1990)
The efficiency of systematic sampling in stereology and its prediction
J. Microsc.
Visuo-oculomotor capabilities of hemidecorticate patients
Soc. Neurosci. Abstr.
Cited by (21)
Impact of prebiotics on metabolic and behavioral alterations in a mouse model of metabolic syndrome
2017, Brain, Behavior, and ImmunityCitation Excerpt :ArcN, CA1, CA3 and DG boundaries were drawn on every sixth section and the first was randomly chosen. Each structure volume was calculated using the formula “V(XX) = ∑Std”; where “∑S” is the sum of surface areas (μm2), “t” the average section thickness and “d” the distance between the sections (Théoret et al., 1999). “t” was estimated to 10 μm after immunohistochemistry processing and guard zones of 2 μm were used to ensure that section top and bottom were never included in the analysis.
Comparison of unbiased estimation of neuronal number in the rat hippocampus with different staining methods
2015, Journal of Neuroscience MethodsCitation Excerpt :CE is the coefficient of error, and calculated with the formula (see Table 2). CE less than 0.1 indicate that reliable estimates were obtained from each animal (Braendgaard et al., 1990; Théoret et al., 1999). Data analysis was performed using paired t-tests.
Nutritional n-3 PUFAs deficiency during perinatal periods alters brain innate immune system and neuronal plasticity-associated genes
2014, Brain, Behavior, and ImmunityAsymmetry in parkinsonism, spreading pathogens and the nose
2012, Parkinsonism and Related DisordersIGF-1 signaling reduces neuro-inflammatory response and sensitivity of neurons to MPTP
2009, Neurobiology of AgingCitation Excerpt :A neuron was counted if more than half the cell body was inside the two consecutive boundaries taken into account. To estimate the number of TH-ir neurons we used: N = V(SNc) (ΣQ−/ΣV(dis)); where N is the estimation of the number of TH-ir neurons, V the volume of the SNc, ΣQ− the number of cells counted in the frames, and ΣV(dis) is the total volume of the frames (Theoret et al., 1999). Mean estimated number of neurons and SEM were then calculated for each group (WT or +/−/NaCl; WT or +/−/MPTP).
Differential behavioral effects of partial bilateral lesions of ventral tegmental area or substantia nigra pars compacta in rats
2008, NeuroscienceCitation Excerpt :In the SNc, dissectors (80 μm length, 60 μm width) were separated from each other by 50 μm (x) and 40 μm (y); and in the VTA dissectors (120 μm length, 80 μm width) were separated from each other by 75 μm (x) and 65 μm (y). The following formula was used to estimate the number of TH-IR neurons: N=V(SNc) (ΣQ−/ΣV(dis)); where N is the estimation of cell number, V is the volume of the SNc or VTA, ΣQ− is the number of cells counted in the dissectors, and ΣV(dis) is the total volume of all the dissectors (Theoret et al., 1999). Mean estimated number of neurons and S.E.M. were then calculated for each group.