Cell Stem Cell
Volume 10, Issue 2, 3 February 2012, Pages 115-119
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The Potential of Stem Cells as an In Vitro Source of Red Blood Cells for Transfusion

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Recent advances have increased excitement about the potential for therapeutic production of red blood cells (RBCs) in vitro. However, generation of RBCs in the large numbers required for transfusion remains a significant challenge. In this article, we summarize recent progress in producing RBCs from various cell sources, and discuss the hurdles that remain for translation into the clinical arena.

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