Trends in Parasitology

Trends in Parasitology

Volume 36, Issue 9, September 2020, Pages 719-721
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Spotlight
A Way Straight-Forward for Leishmania Genetics

https://doi.org/10.1016/j.pt.2020.07.005Get rights and content

Genetic exchange between Leishmania parasites was demonstrated in sandflies over 10 years ago. Louradour et al. have shown in vitro hybridization of two Leishmania tropica isolates, with the potential to remove a major roadblock to using forward genetics in Leishmania, understanding Leishmania reproductive biology, and analyzing gene flow in natural populations.

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Acknowledgments

We thank Dr Stephen Doyle and Dr David Sacks for comments on this article. We are funded by the Wellcome Trust via their core funding of the Wellcome Sanger Institute (grant 206194), by the UK Medical Research Council (grant MR/R01020X/1), and by the UK Department for International Development (DFID) under the MRC/DFID Concordat agreement (grant MR/R021600/1).

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