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Medication Effects on EEG Biomarkers in Attention-deficit/Hyperactivity Disorder

Published online by Cambridge University Press:  23 March 2020

M. Cebi ,
N. İsiten ,
B. Metin ,
B. Sütçübaşı  and
N. Tarhan
N. İsiten
Affiliation:
Uskudar University, Faculty of Humanities and Social Sciences, Istanbul, Turkey
B. Metin
Affiliation:
Uskudar University, Faculty of Humanities and Social Sciences, Istanbul, Turkey
B. Sütçübaşı
Affiliation:
Uskudar University, Faculty of Humanities and Social Sciences, Istanbul, Turkey
N. Tarhan
Affiliation:
Uskudar University, Faculty of Humanities and Social Sciences, Istanbul, Turkey

Abstract

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EEG biomarkers have become increasingly used to aid in diagnosis of ADHD. Despite several studies suggesting that EEG theta/beta ratio may help discriminating ADHD from other disorders, the effect of medications on theta/beta ratio is not known. Forty-three children with ADHD that were evaluated with quantitative EEG before and after methylphenidate were included in the study. Theta/beta ratio, theta and beta powers for whole brain, central and frontal areas were calculated. Theta/beta power decreased significantly after treatment; however this change was largely due to an increase in beta power, rather than a fall in theta power. The results suggest that beta power is sensitive to medication effects, while theta power remains as a trait biomarker unaffected by medication status. The value of EEG biomarkers for monitoring neuropsychological performance and clinical status should be explored by future studies.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
e-Poster walk: Child and adolescent psychiatry–part 2
Information
European Psychiatry , Volume 41 , Issue S1: Abstract of the 25th European Congress of Psychiatry , April 2017 , pp. S125
Copyright
Copyright © European Psychiatric Association 2017
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