Discovery of small molecule inhibitors of human uridine-cytidine kinase 2 by high-throughput screening
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Author contributions
A.O.A., A.G and Q.L performed experiments; M.J. and D.A. enabled the HTS campaign at Novartis’ FAST Lab; C.K. supervised the overall project. The manuscript was written through contributions of all authors. All authors have given approval to the final version of the manuscript.
Funding sources
National Institute of Health (NIH), U19 Grant, project number 1U19AI109662, National Institute of Allergy and Infectious Diseases (NIAID), National Science Foundation Graduate Research Fellowship and ChEM-H Chemical Biology Interface Training Program Fellowship.
Acknowledgment
The authors thank Catherine Liou and Donovan Ruiz for assistance with this work.
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Authors contributed equally.
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Present address: Gilead Sciences, 333 Lakeside Dr, Foster City, CA 94404, USA.
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