Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Volume 1865, Issue 9, 1 September 2019, Pages 2368-2378
CD74 knockout attenuates alcohol intake-induced cardiac dysfunction through AMPK-Skp2-mediated regulation of autophagy
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Abbreviations
AICAR
5′-aminoimidasole-4-carboxamide-1-β-d-ribofuranoside
AMPK
5′ adenosine monophosphate-activated protein kinase
DHE
dihydroethidium
− dL/dt
maximal velocity of relengthening
+ dL/dt
maximal velocity of shortening
EDD
end diastolic dimension
ESD
end systolic dimension
∆FFI
fura-fluorescence intensity change
GFP
green fluorescence Protein
IL
interleukin
LV
left ventricle
MIF
migration inhibitory factor
mTOR
mechanistic target of rapamycin
NCM
Neonatal cardiomyocyte
PS
peak shortening
Sirt
sirtuin
Skp2
S-phase kinase-associated protein 2
TEM
Transmission electron microscopy
TPS
time-to-peak shortening
TR90
time-to-90% relengthening
WT
Wild type
Keywords
CD74
Ethanol
Cardiomyocyte
Autophagy
AMPK
Skp2
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