Original articleLeft ventricular regional function and relaxation: Effects of inotropic stimulation☆
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Cited by (5)
Effects of milrinone versus epinephrine on left ventricular relaxation after cardiopulmonary bypass following myocardial revascularization: Assessment by color M-mode and tissue doppler
2005, Journal of Cardiothoracic and Vascular AnesthesiaMilrinone, not epinephrine, improves left ventricular compliance after cardiopulmonary bypass
2000, Journal of Cardiothoracic and Vascular AnesthesiaCitation Excerpt :During separation from CPB, catecholamines may produce increases in heart rate by stimulation of β-receptors or induce coronary vasoconstriction. In the absence of heart disease, the addition of epinephrine improves ventricular relaxation during rapid pacing22; in patients at risk for myocardial ischemia, however, catecholamines may decrease ventricular compliance.23 Compared with β-agonists, phosphodiesterase III inhibitors can improve diastolic function in several ways; they appear not to have the same chronotropic effects as catecholamines,24 and ventricular emptying is facilitated at a lower wall tension, whereas coronary blood flow is increased.25,26
Dobutamine stress Doppler echocardiography: Reproducibility and physiologic left ventricular filling patterns
1997, International Journal of CardiologyEvaluation and treatment of diastolic dysfunction
2001, Progress in Anesthesiologyβ-Adrenergic stimulation enhances left ventricular diastolic performance in normal subjects
1997, Journal of Cardiovascular Pharmacology
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Supported in part by Grants G8002204SA and G8306850 from the Medical Research Council, United Kingdom. Dr Lehot was the recipient of a MRC/INSERM fellowship.