ArticleCardiovascular responses to blockade of GABA synthesis in the hypothalamus of the spontaneously hypertensive rat
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Cited by (26)
Daily exercise normalizes the number of diaphorase (NOS) positive neurons in the hypothalamus of hypertensive rats
2002, Brain ResearchCitation Excerpt :These data document a neurogenic etiology for hypertension in the SHR and identify the hypothalamus as a potential region for maintaining the hypertensive state [23,40,50,70]. There is considerable evidence that a deficit in the inhibitory neurotransmitter, δ-aminobutyric acid (GABA), in the hypothalamus contributes to the sympatho-excitatory, hypertensive state in the SHR [15,28,58,59]. For example, GABA levels and turnover rates are lower in the hypothalamus of SHR [15,28,41,58].
Chronic exercise increases GAD gene expression in the caudal hypothalamus of spontaneously hypertensive rats
2001, Molecular Brain ResearchHypothalamus, hypertension, and exercise
2000, Brain Research BulletinGABAB-ergic stimulation in hypothalamic pressor area induces larger sympathetic and cardiovascular depression in spontaneously hypertensive rats
1996, American Journal of Hypertension
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