Automated localization of the prostate at the time of treatment using implanted radiopaque markers: Technical feasibility

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    Numerous studies have demonstrated quantifiable interfraction prostatic motion, both in general and in relation to the pelvic bones, and to account for this, image guided radiation therapy (IGRT) is often used (9-13). Implantation of fiducial seeds (intraprostatic markers or IPMs) into the prostate allows localization on orthogonal x-ray images or cone-beam CTs (CBCTs) (14-16). The IPMs on the planning and daily images can be aligned using rigid registration (RR).

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