252Cf plasma desorption fourier transform mass spectrometry of involatile compounds

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Abstract

A 50 μCi 252Cf source in a Fourier transform mass spectrometer produces structurally characteristic spectra for compounds of molecular weights up to 2000. As found for plasma desorption ionization with time-of-flight instruments, use of the substrate, nitrocellulose, and the adduct, glutathione, greatly increase sensitivities. Ion collection times of 1–2 min and the elimination of the cell ion quenching event dramatically increase the sensitivity as well as the relative abundance of the molecular ion.

References (27)

  • M.B. Comisarow et al.

    Chem. Phys. Lett.

    (1974)
  • B.T. Chait et al.

    Int. J. Mass Spectrom. Ion Processes

    (1985)
  • Md.A. Mabud et al.

    Int. J. Mass Spectrom. Ion Processes

    (1985)
  • R.B. Cody et al.

    Anal. Chim. Acta

    (1985)
  • D.A. Laude et al.

    Mass Spectrom. Rev.

    (1986)
  • R.B. Cody et al.

    Proc. Natl. Acad. Sci. U.S.A.

    (1985)
  • A.G. Marshall

    Acc. Chem. Res.

    (1985)
  • C.L. Wilkins et al.

    Anal. Chem.

    (1985)
  • I.J. Amster et al.

    Anal. Chem.

    (1987)
  • D.H. Russell

    Mass Spectrom. Rev.

    (1986)
  • D.F. Hunt et al.

    Proc. Natl. Acad. Sci. U.S.A.

    (1987)
  • R.D. Macfarlane

    Acc. Chem. Res.

    (1982)
  • Cited by (0)

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