EEG sleep of young adults with major depression: a controlled study

doi:10.1016/0165-0327(91)90089-B

Journal of Affective Disorders

Volume 22, Issues 1–2, May–June 1991, Pages 91-100

https://doi.org/10.1016/0165-0327(91)90089-B Get rights and content

Abstract

The EEG sleep of 75 subjects aged 16–25 years was studied. Thirty-eight were in an episode of RDC major depression, and 37 were normal controls. Only one sleep continuity measure differed between the two groups: sleep latency was significantly longer in the depressive group. REM period latencies and other sleep variables did not differ between the groups. Subgroup analyses, within the depressed group with respect to inpatient status, revealed significantly higher REM density (P < 0.03) and a marginally shortened REM period latency (P < 0.07) among the inpatient depressives. Subgroup analysis across suicidal ratings revealed a significantly higher REM density (P < 0.04) among suicidal depressives. Severity estimates of depression did not correlate with sleep findings. These results parallel another recent report on adolescent depressed subjects, suggesting that inpatient and/or suicidal status is an important variable in the expression of EEG sleep abnormalities in the adolescent/young adult age group.

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^☆: This article was essentially completed shortly before the untimely death of Joaquim Puig-Antich, M.D., and is dedicated to Kim and his work.

^∗: Present addresses: G.M. Asnis, Department of Psychiatry, Albert Einstein College of Medicine, New York, NY; R.E. Dahl, N.D. Ryan and B. Nelson, Division of Child and Adolescent Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA; H. Rabinovich, Eastern Pennsylvania Psychiatric Institute, Philadelphia, PA, U.S.A.

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EEG sleep of young adults with major depression: a controlled study☆

Abstract

J. Affect. Disord.

J. Affect. Disord.

J. Affect. Disord.

J. Affect. Disord.

J. Affect. Disord.

Psychiatr. Res.

J. Affect. Disord.

Psychiatr. Res.

Psychiatr. Res.

J. Psychiatr. Res.

Biol. Psychiatry

J. Affect. Disord.

Affective disorders in referred children and younger siblings of manic-depressives

Arch. Gen. Psychiatry

The sleep of dysthymic patients: a comparison with normal controls

Biol. Psychiatry

Age of onset and genetic transmission of affective disorders

Acta Psychiatr. Scand.

Recurrent and noncurrent depression: a family study

Arch. Gen. psychiatry

Sleep markers for major depressive disorder in adolescent patients

Sleep Res.

The assessment of affective disorders in children and adolescents by semi-structured interview

Arch. Gen. Psychiatry

EEG sleep and clinical characteristics in young primary depressives

Sleep Res.

EEG sleep of healthy children. I: Findings using standard measurement methods

Sleep

EEG sleep of healthy children. II: Findings using automated delta and REM sleep measurement methods

Sleep

Sleep EEG findings in depressed children and adolescents

Am. J. Psychiatry

Children with major depression show reduced rapid eye movement latencies

Arch. Gen. Psychiatry

A diagnostic interview

Arch. Gen. Psychiatry

Hamilton Depression Rating Scale: extracted from regular and change versions of the Schedule for Affective Disorders and Schizophrenia

Arch. Gen. Psychiatry

Reduced rapid eye movement latency: a predictor of recurrence in depression

Neuropsychopharmacology

Successful separation of depressed, normal and insomniac subjects by EEG sleep data

Arch. Gen. Psychiatry

The EEG sleep of adolescents with major depression and normal controls

Arch. Gen. Psychiatry

Extended sleep (hypersomnia) in young depressed patients

Am. J. Psychiatry

Early- and late-onset bipolar affective disorder. A genetic study

Arch. Gen. Psychiatry

The sleep profile in manic-depressive patients in the depressive phase: sleep studies to compare these patients with healthy human subjects

Waking Sleeping

EEG sleep in depressed adolescents

Am. J. Psychiatry