Cell
ArticleMolecular characterization of a swelling-induced chloride conductance regulatory protein, plCIn
References (41)
- et al.
Identification of calmodulin-binding proteins
Meth. Enzymol.
(1990) - et al.
Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface
Cell
(1992) - et al.
Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein
Cell
(1992) - et al.
The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication
Cell
(1993) The cell cytoskeleton: possible role in volume control
Curr. Topics Membr. Trans.
(1987)- et al.
Activation of ion transport pathways by changes in cell volume
Biochim. Biophys. Acta
(1991) One-step purification of hybrid proteins which have β-galactosidase activity
Gene
(1984)- et al.
Hypotonicity activates a native chloride current in Xenopus oocytes
J. Gen. Physiol.
(1994) - et al.
Anisosmotic cell volume regulation: a comparative view
Am. J. Physiol.
(1989) - et al.
Alternate pathways for chloride conductance activation in normal and cystic fibrosis airway epithelial cells
Am. J. Physiol.
(1992)
Human Sos1: a guanine nucleotide exchange factor for ras that binds to GRB2
Science
Translation of eukaryotic messenger RNA in Xenopus oocytes
Volume-sensitive chloride conductance in bovine chromaffin cell membrane
J. Physiol.
Association of sos ras exchange protein with GRB2 is implicated in tyrosine kinase signal transduction and transformation
Nature
Involvement of calcium and cytoskeleton in gallbladder epithelial cell volume regulation
Am. J. Physiol.
Regions involved in the opening of CIC-2 chloride channel by voltage and cell volume
Nature
Membrane mechanisms in volume and pH regulation in vertebrate cells
Physiol. Rev.
Swelling-activated KCl co-transport in rabbit red cells: flux is determined mainly by cell volume rather than shape
Am. J. Physiol.
Volume-regulatory CI-channel currents in cultured human epithelial cells
J. Physiol.
Properties and regulation of chloride channels in cystic fibrosis and normal airway cells
Pflügers Arch.
Cited by (196)
Molecular Identities and ATP Release Activities of Two Types of Volume-Regulatory Anion Channels, VSOR and Maxi-Cl
2018, Current Topics in MembranesCitation Excerpt :Furthermore, pICln was later shown to be a spliceosome component (Pu, Krapivinsky, Krapivinsky, & Clapham, 1999). On the other hand, pICln was found to modulate VSOR activity in a number of cell types (Chen, Wang, & Jacob, 1999; Gschwentner et al., 1995; Hubert et al., 2000; Krapivinsly et al., 1994). pICln is known to form complexes with soluble actin and other cytosolic proteins (Krapivinsky, Ackerman, Gordon, Krapivinsky, & Clapham, 1994) and also interact with a homolog of the p21-activated protein kinases (PAKs) which is involved in cytoskeletal rearrangements (Krapivinsky, Pu, Wickman, Krapivinsky, & Clapham, 1998).
The Function of Survival Motor Neuron Complex and Its Role in Spinal Muscular Atrophy Pathogenesis
2017, Spinal Muscular Atrophy: Disease Mechanisms and TherapyIdentification of Methylosome Components as Negative Regulators of Plant Immunity Using Chemical Genetics
2016, Molecular PlantCitation Excerpt :pICln may also play a role in maintaining cellular osmotic homeostasis during cell swelling by inducing chloride conductance (Sardini et al., 2003). Interestingly, pICln was not detected on the plasma membrane in MDCK cells using immunofluorescent staining (Krapivinsky et al., 1994), suggesting pICln to be a channel regulator rather than a channel itself. The anchor-insertion channel hypothesis may help explain these seeming controversial observations that pICln is mainly cytosolic but might be inserted into the plasma membrane under certain conditions (Strange, 1998).
The molecular and functional interaction between ICln and HSPC038 proteins modulates the regulation of cell volume
2011, Journal of Biological ChemistryRole of pICLn in methylation of Sm proteins by PRMT5
2009, Journal of Biological ChemistryAnion Channels
2008, Seldin and Giebisch's The Kidney
- ★
The first two authors contributed equally to this work.