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Cited by (139)
Enhanced perceptual task performance without deprivation in mice using medial forebrain bundle stimulation
2022, Cell Reports MethodsCitation Excerpt :Therefore, for the majority of studies focused on sensory or motor behaviors and not motivation or reward per se, MFB stimulation is unlikely to modify the results of interest and provides a way to avoid the side effects of deprived states. MFB stimulation evokes dopamine release in the NA28 and pharmacologically increasing or reducing dopamine levels increases or reduces MFB stimulation efficacy respectively.29 Although the MFB contains dopaminergic fibers essential for instrumental behavior,30 it has been shown that the physiology of MFB self-stimulation is incompatible with a direct recruitment of these fibers to drive reward.31
Operant responding: Beyond rate and interresponse times
2022, Brain Research BulletinDual roles of dopamine in food and drug seeking: The drive-reward paradox
2013, Biological PsychiatryCitation Excerpt :Similarly, both are facilitated by delta-9 tetrahydrocannabinol (57–59). While amphetamine is an anorexigenic drug, even it potentiates aspects of stimulation-induced feeding (60), as well as brain stimulation reward (61), particularly when it is microinjected into nucleus accumbens (62,63). How do the first-stage fibers of brain stimulation reward interact with the dopamine system?
Concurrent stimulation-induced place preference in lateral hypothalamus and parabrachial complex: Differential effects of naloxone
2011, Behavioural Brain ResearchCitation Excerpt :In this context, recent studies in our laboratory indicated the likely involvement of the endogenous opioid system in the reward induced by electrical stimulation of the LPBe [25]. Intracranial self-stimulation (ICSS) behavior induced in the MFB has been related to dopaminergic ([6], for a review [23,41–46]) and opioid systems [41,47]. With regard to the opioid system, controversial results have been obtained by studies using antagonists such as naloxone in operant tasks ([47], for a review [48–50]).