Elsevier

Urology

Volume 30, Issue 6, December 1987, Pages 583-585
Urology

Hemorrhagic urethritis in female-to-male transsexual: Possible androgen-related phenomena

https://doi.org/10.1016/0090-4295(87)90443-2Get rights and content

Abstract

This article describes a case of hematuria and urethritis related to androgen stimulation in a female-to-male transsexual receiving testosterone cypionate. Biopsy of the affected urethral tissue revealed periurethral glands which demonstrated a strong positive reaction with immunoperoxidase staining for prostatic specific antigen. When the androgen stimulus was reduced, the patient's symptoms resolved. This report gives evidence for possible androgen-induced pathology in the female urethra.

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