Structural comparisons of wild-type and nuclear transport-defective simian virus 40 large tumor antigens
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Nuclear localization of Merkel cell polyomavirus large T antigen in Merkel cell carcinoma
2010, VirologyCitation Excerpt :The in vivo expression findings for MCPyV-LT antigen in MCC cells suggested that nuclear localization is common among MCC cases. It has also been demonstrated that SV40-LT antigen is localized in the nuclei of infected cells and transfectants (Jarvis et al., 1984; Kalderon et al., 1984). Transfection experiments using CV-1 cells revealed that RFP-tagged MCPyV-LT antigen was expressed in the nucleus with a diffuse staining pattern, whereas vector-transfected cells expressed RFP in the cytoplasm (Fig. 2A).
Nuclear location signal-mediated protein transport
1989, BBA - Gene Structure and ExpressionThe plasma-membrane-associated form of SV40 large tumor antigen: biochemical and biological properties
1986, BBA - Reviews on Cancer
Copyright © 1984 Published by Elsevier Inc.