Elsevier

Atherosclerosis

Volume 37, Issue 4, December 1980, Pages 625-629
Atherosclerosis

Research paper
Clofibrate raises plasma apoprotein A-I and HDL-cholesterol concentrations

https://doi.org/10.1016/0021-9150(80)90069-6Get rights and content

Abstract

In 10 hyperlipidaemic subjects who had been satisfactorily treated with clofibrate, stopping treatment led to significant reductions in plasma apoprotein A-I and high density lipoprotein cholesterol concentrations; resumption of treatment significantly raised both. The changes were therefore inversely related to those in the plasma cholesterol and triglyceride levels and were most prominent in hypertriglyceridaemic subjects.

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This work was supported by a grant from the National Health and Medical Research Council of Australia.

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