Elsevier

Brain Research

Volume 462, Issue 1, 11 October 1988, Pages 194-198
Brain Research

Burst firing induced in midbrain dopamine neurons by stimulation of the medial prefrontal and anterior cingulate cortices

https://doi.org/10.1016/0006-8993(88)90606-3Get rights and content

Abstract

Extracellular recordings were obtained from mesencephalic dopamine neurons in urethane-anesthetized rats. A population of neurons responded to electrical stimulation of the frontal cortex with bursts of action potentials. These bursts resembled those that occur spontaneously in midbrain dopamine neurons with regard to length, interspike interval and post-burst inhibition. This is the first afferent input known to elicit bursting in dopamine neurons.

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