Elsevier

Brain Research

Volume 335, Issue 1, 27 May 1985, Pages 182-187
Brain Research

Ventral rhizotomy enhances regeneration of uninjured sensory neurons

https://doi.org/10.1016/0006-8993(85)90292-6Get rights and content

Abstract

Uninjured sensory neurons show metabolic and morphologic changes, as well as enhanced regeneration, when exposed to adjacent degenerating ventral root fibers. The release of a neurotrophic factor from the degenerating nerve fibers may be responsible for ‘priming’ the uninjured neuron and thereby enhancing its response to injury.

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This work was supported by NIH Grants HL20604 and NS18071.

1

We thank Dr. Henry Yip, Dr. Robert Schmidt, Patricia Osborne, and Pat Lampe for the advice and assistance.

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