Elsevier

Brain Research

Volume 273, Issue 2, 29 August 1983, Pages 335-339
Brain Research

Cytoarchitectonic distribution of zinc in the hippocampus of man and the rat

https://doi.org/10.1016/0006-8993(83)90858-2Get rights and content

Abstract

Zinc was measured in whole hippocampus and in hippocampal sub-regions by stable-isotope dilution mass spectrometry. In both man and the rat, the most zinc (102–145 ppm, dry weight) was found in the hilar region, the least (27–37) in the fimbria. The amount of zinc directly associated with mossy-fiber axons was estimated to be approximately 8% of the total zinc in the hippocampus, and the concentration of mossy-fiber zinc was estimated at 220–300 μM. Methodological and theoretical implications of the quantitative findings were discussed.

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