Issues in Infectious DiseaseFever of unknown origin (FUO) and a renal mass: Renal cell carcinoma, renal tuberculosis, renal malakoplakia, or xanthogranulomatous pyelonephritis?
Section snippets
Case Report
A 68-year-old woman presented with fevers, generalized weakness, and sweats of a month’s duration. She also reported decreased appetite and a 20-pound involuntary weight loss during the previous 8 months. During her childhood, she had received BCG, and has been purified protein derivative (PPD)-positive ever since. A physical examination was unremarkable, except for left-flank tenderness. Her leukocyte (WBC) count was 14.1 K/mm3 (73% neutrophils, 18% lymphocytes, and 7% monocytes), and her
Discussion
In patients with an FUO and a renal mass, the most common disorder, far and away, is revealed to be renal cell carcinoma.1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 Patients with renal TB usually have radiologic abnormalities involving both the upper and lower genitourinary (GU) tracts, and these provide a clue to the diagnosis. Patients with renal TB often present with sterile pyuria with or without microscopic hematuria, with a urine pH of less than 5.5. Renal calcifications are usually present in
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2014, Surgical Pathology ClinicsCitation Excerpt :XGP manifesting as a localized mass is often preoperatively misdiagnosed as RCC because of nonspecific imaging features. Recent case reports continue to describe this diagnostic challenge.15,16 Grossly, the presence of renal obstruction with staghorn calculi and dilated calices with adjacent yellow-orange parenchymal replacement are suggestive of an inflammatory rather than a malignant lesion.
An unusual association of renal cell carcinoma and renal malakoplakia with focal segmental glomerulosclerosis in an elderly patient
2018, Indian Journal of NephrologyFrameworks for Internal Medicine
2018, Frameworks for Internal MedicineEarly progression of xanthogranulomatous pyelonephritis in children might be dependent on vimentin expression
2017, American Journal of Case ReportsXanthogranulomatous pyelonephritis presenting as a pseudotumour in a 5-year-old boy
2012, BMJ Case Reports