Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Volume 1833, Issue 2, February 2013, Pages 286-294
ReviewControl of protein synthesis in yeast mitochondria: The concept of translational activators☆
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Highlights
► The mitochondrial translation system is very different from that of bacteria or eukaryotic cytosol. ► In yeast, protein synthesis depends on mRNA-specific translational activators. ► Feedback loops ensure that only proteins that can be assembled are synthesized. ► This avoids the accumulation of potentially harmful assembly intermediates.
Keywords
Cytochrome c oxidase
Mitochondrial translation
Protein insertion
Ribosome
Translational activator
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This article is part of a Special Issue entitled: Protein import and quality control in mitochondria and plastids.
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